Hyalgan® (Hyaluronic Acid) Injections

Natural Support for Joint Lubrication & Knee Comfort

Hyalgan® is an FDA-approved hyaluronic acid (HA) injection used to support lubrication, cushioning, and overall comfort within the knee joint. Hyaluronic acid is a natural component of joint fluid that helps reduce friction and maintain smooth, comfortable movement. Over time, age and osteoarthritis may cause HA levels to decline, leading to stiffness, inflammation, and reduced mobility.

At Sikora Integrative Medicine, Hyalgan injections are part of our orthobiologic treatment options for patients seeking a non-surgical approach to knee osteoarthritis. The treatment is designed to improve joint function and reduce symptoms without the downtime or risks associated with more invasive procedures.

Regenerative Medicine

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Key Benefits of Hyalgan® Therapy

Hyalgan replenishes natural hyaluronic acid within the knee, offering multiple joint-supporting benefits.

Benefits may include:

  • Enhanced joint lubrication and reduced friction
  • Improved shock absorption and cushioning
  • Reduced knee pain associated with osteoarthritis
  • Improved mobility and function
  • Non-surgical alternative to corticosteroid injections
  • May delay or avoid the need for knee replacement

Hyalgan is often chosen by patients seeking relief without recurring steroid use or more invasive treatments.

How Hyalgan® Works

Hyaluronic acid helps restore the quality of synovial fluid
, the natural lubricant inside the knee. By improving fluid thickness and elasticity, Hyalgan may help the joint move more comfortably and decrease mechanical stress on cartilage.

Some patients use Hyalgan alone, while others combine it with PRP, physical therapy, or supportive lifestyle strategies for enhanced results.

Conditions Treated with Hyalgan®

Hyalgan may be recommended for:

  • Knee osteoarthritis (mild to moderate):
    Hyalgan provides additional joint lubrication, which may help improve comfort and mobility in knees affected by
    cartilage wear.
  • Chronic knee stiffness:
    By enhancing the knee’s natural fluid environment, Hyalgan may help reduce stiffness and support smoother
    movement.
  • Reduced joint lubrication:
    As a hyaluronic acid–based injection, Hyalgan may help restore cushioning and ease friction within the joint.
  • Pain aggravated by walking, stairs, or activity:
    Improved lubrication and shock absorption from Hyalgan may help lessen discomfort during routine or high-demand
    movements.
  • Early degenerative joint changes:
    Hyalgan may help support joint function and comfort as tissues begin to show signs of age-related wear and tear.

Your provider will determine whether Hyalgan is suitable based on imaging and examination results.

What to Expect During Hyalgan Therapy

Hyalgan injections are performed in the office and typically take 15–20 minutes to complete.

Step-by-step:

1

Preparation

Your provider will conduct a physical exam and review imaging to determine if Hyalgan is suitable for your level of osteoarthritis.

2

Injection

Hyalgan is injected directly into the knee joint using sterile technique. Ultrasound guidance may be used to ensure accurate placement of the needle.

3

Recovery

Most patients resume their regular activities on the same day. Mild soreness or swelling may occur temporarily.

4

Treatment Plan

Hyalgan is typically administered as a series of injections, commonly one injection per week for 3–5 weeks, depending on your individual treatment plan.

When to Expect Results

Results develop gradually as the hyaluronic acid improves the joint environment.

Typical improvement timeline:

  • Initial relief: 2–4 weeks
  • Notable improvement: 4–8 weeks
  • Peak benefit: 3–6 months

Many patients repeat treatment every 6–12 months to maintain results.

Who Is a Good Candidate for Hyalgan® (Hyaluronic Acid) Injections?

Hyalgan may be suitable for individuals experiencing knee joint discomfort associated with osteoarthritis or age-related cartilage wear. It is often considered when symptoms persist despite physical therapy, activity modification, or over-the-counter options.

Candidates typically include adults seeking a non-surgical way to improve joint cushioning, reduce stiffness, and enhance mobility. Your provider will evaluate your exam findings, imaging, and goals to determine whether Hyalgan® is a suitable option for you.

Why Choose Sikora Integrative Medicine

We offer a thoughtful and personalized approach to joint care, prioritizing treatments that are safe, effective, and tailored to your specific needs. Our team pairs evidence-informed therapies with clear guidance to help you make confident decisions about your health.

What sets us apart:

  • Individualized treatment planning based on your symptoms and functional goals
  • Compliance-driven musculoskeletal care aligned with current safety standards
  • Access to diagnostic tools such as musculoskeletal ultrasound and specialty lab testing
  • A patient-centered experience with thorough education and consistent follow-up
  • A welcoming, supportive environment focused on long-term joint health
Frequently Asked Questions

Hyalgan provides lubrication and cushioning, while PRP delivers growth factors to support tissue healing and regeneration. Some patients combine both treatments for enhanced results.

Many patients experience relief for 6–12 months, depending on their level of activity and the severity of their osteoarthritis.

Yes. Hyalgan is FDA-approved and has a long history of use in managing knee osteoarthritis.

While results vary, many patients use Hyalgan to delay or avoid knee replacement by improving function and reducing pain.

Some insurance plans cover hyaluronic acid injections. Your provider will review eligibility and cost during your consultation.

Schedule Your Consultation Today

We’re here to answer your questions, review your goals, and help you determine the most
appropriate treatment options. Our team provides personalized guidance so you feel confident in your next steps. Flexible financing through
M Lend Financial, is available, making advanced care more accessible.

Disclaimer:This information is provided for educational purposes only and is not intended to be medical advice. It should not be used to diagnose, treat, or cure any condition. Always consult your healthcare provider for personalized guidance. Services are available exclusively to Florida residents.